Almost every day I see someone post and ask questions about what products to run, for how long, what doses, what to expect and what are the side effects.
I can understand how this could become confusing, with all the different responses especially for someone new to this lifestyle. (Beginner) so we will go over some basic info with you and hopefully this will help you understand a little better.
First thing is plan ahead make sure you have everything you need in hand before you begin. Also make sure to use a reliable source.
I highly recommend having blood work done before your cycle, during and after your PCT to assure your levels return to normal ,unless your on TRT. Then return to your trt dose after cycle. A pct will not be necessary although I highly recommend using an all in one support supplement(cheaper in price)to help mitigate and/or regulate any possible side effects.
So What is considered a normal first cycle
500-600 mg a week. Divided into 2 doses.
Monday and Thursday
Arimidex 0.5-1.0mg eod or Aromasin 12.5 -25mg daily
HCG if you choose 500iu X2
The reasons you take your test like this is to provide stable blood levels.
When injecting long esters like cypionate or Enanthate with this frequency I tend to have less side effects then once a week injections.
You wanna keep everything nice and even , not like a roller coaster going up then down over and over. This will cause more side effects and they will be harder to control.
There are a number of esters which provide varying release times. Acetate or propionate esters extend the release time of testosterone a couple of days. deconate ester prolongs the release of test about 3 weeks. Testosterone enanthate and cypionate are almost identical esters. The use of an ester allows for a less frequent injection schedule than using a water based testosterone like suspension which has no ester at all and is rapidly in and out of your system after injection. The published release times are not exact and are many times based on a single injection not many multiple injections which can delay the release of the hormone. Other factors affect release times of esters such as scar tissue and the muscle group injected. Only a blood test can confirm when the active hormone has cleared your system.
Esters not only effect release times but also the potency of the Testosterone as esters make up part of the steroid weight. This must be taken into account when calculating dosages. The longer the release time the less free hormone. For example propionate is about 15% more potent mg. for mg. then enanthate. So 500mg of propionate would equal about 575 mg. of enanthate.
Along with your testosterone you wanna take an AI.
Aromatase Inhibitor
Arimidex or Aromasin should be used on cycle to control and regulate your Estrogen. This will also help to keep free testosterone levels high.
0.5mg-1mg Arimidex eod OR 10-25mg Aromasin daily is recommended. Start with the lower dose and adjust as necessary. This can have an affect on water retention, your blood pressure, and libido. Please make adjustments as needed. Blood work is crucial for accuracy to make the proper adjustments. Free T should be in the high range and estradiol 10-25 pg/ml.
Serm
Keep nolvadex/tamoxifen on hand in case of emergency or you believe your suffering from gyno symptoms. Doses may range from 10-40mg daily depending on your test doses being used and how your body responds. Individuals will respond differently.
Human Chorionic Gonadotropin
A simple way to restore ITT levels and maintain the mass of the testes is to administer HCG during testosterone treatment. During a study it was determined that HCG is dose dependant and that approximately 300iu HCG taken every other day equal to 1,050iu HCG weekly.
I would recommend 500iu twice a week while on test.
Testosterone dose-response relationships in healthy young men
pubmed.ncbi.nlm.nih.gov
Below is some info and stats from the study.
The only two groups that reported significant muscle building benefits were the 300 and 600 mg groups so any dose lower than 300mg will not be considered in this essay. 12 men participated in the 300 mg group and 13 men in the 600 mg group.
600mg of Testosterone a week for 20 weeks resulted in the following benefits. Increased fat free mass, muscle strength, muscle power, muscle volume, hemoglobin and IGF-1.
The same 600 mg administration resulted in 2 side effects. HDL cholesterol was negatively correlated and 2 men developed acne.
The normal range for total T in men is 241-827 ng/dl according to Labcorp and 260-1000 ng/dl according to Quest Laboratories. The normal range for IGF-1 is 81-225 according to Labcorp. Total T and IGF-1 levels were taken after 16 weeks and resulted in the following;
Total Testosterone
300 mg group-1,345 ng/dl a 691 ng increase from baseline
600 mg group-2,370 ng/dl a 1,737 ng increase from baseline
IGF-1
300 mg group-388 ng/dl a 74 ng increase from baseline
600 mg group-304 ng/dl a 77 ng increase from baseline
Body composition was measured after 20 weeks.
Fat Free Mass by underwater weighing
300 mg group-5.2kg (11.4lbs) increase
600 mg group-7.9kg (17.38lbs) increase
Fat Mass by underwater weighing
300 mg group-.5kg (1.1lbs) decrease
600 mg group-1.1kg (2.42lbs) decrease
Thigh Muscle Volume
300 mg group-84 cubic centimeter increase
600 mg group-126 cubic centimeter increase
Quadriceps Muscle Volume
300 mg group-43 cubic centimeter increase
600 mg group-68 cubic centimeter increase
Leg Press Strength
300 mg group-72.2kg (158.8lbs) increase
600 mg group-76.5kg (168.3lbs) increase
Leg Power
300 mg group-38.6 watt increase
600 mg group-48.1 watt increase
Hemoglobin
300 mg group-6.1 gram per liter increase
600 mg group-14.2 gram per liter increase
Plasma HDL Cholesterol
300 mg group-5.7 mg/dl decrease
600 mg group-8.4 mg/dl decrease
Acne
300 mg group-7 of the 12 men developed acne
600 mg group-2 of the 13 men developed acne
no significant changes in PSA or liver enzymes at any dose up to 600mg. However, long-term effects of androgen administration on the prostate, cardiovascular risk, and behavior are unknown. The study shows that there is a dose dependant relationship with testosterone administration. But keep in mind the more test your taking the greater the muscle building effects but also the greater chances of potential side effects.
An example of a cycle would look like this.
Monday 300mg Test E /12.5mg Asin (hcg500iu)
Tuesday 12.5mg Asin
Wednesday 12.5mg Asin
Thursday 300mg Test E/ 12.5mg Asin
Friday 12.5mg Asin (hcg500iu)
Saturday 12.5mg Asin/
Sunday 12.5mg Asin
If you choose to run HCG ?
PCT post cycle therapy
AI should be used as long as there is an aromatizing compound being administered. Testosterone and HCG aromatize therefore it is recommended to use an AI until they clear your system. Nolva has been shown to reduce IGF-1 and GH levels when used alone. On cycle this is not a big deal because testosterone increases IGF-1 in a dose dependant relationship. However off cycle this is a problem. PCT is a critical time and lower IGF-1 and GH levels is not something you wanna do. I am recommending an AI that is specific to men that can be used on cycle and during PCT. Aromasin is my definite choice..
Sample PCT protocol for long esters like Test C and Test E
100/100/100/50 Clomid
20mg/20mg/10mg/10mg Aromasin
3g Vit C every day
10g creatine daily
References
Testosterone dose-response relationships in healthy young men;
pubmed.ncbi.nlm.nih.gov
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males
academic.oup.com
Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression
pubmed.ncbi.nlm.nih.gov
Use of clomiphene citrate to reverse premature andropause secondary to steroid abuse.
https://pubmed.ncbi.nlm.nih.gov/125...citrate, with multiple anabolic steroid abuse.
Hope this help some people.
Thanks macedog24
I can understand how this could become confusing, with all the different responses especially for someone new to this lifestyle. (Beginner) so we will go over some basic info with you and hopefully this will help you understand a little better.
First thing is plan ahead make sure you have everything you need in hand before you begin. Also make sure to use a reliable source.
I highly recommend having blood work done before your cycle, during and after your PCT to assure your levels return to normal ,unless your on TRT. Then return to your trt dose after cycle. A pct will not be necessary although I highly recommend using an all in one support supplement(cheaper in price)to help mitigate and/or regulate any possible side effects.
So What is considered a normal first cycle
500-600 mg a week. Divided into 2 doses.
Monday and Thursday
Arimidex 0.5-1.0mg eod or Aromasin 12.5 -25mg daily
HCG if you choose 500iu X2
The reasons you take your test like this is to provide stable blood levels.
When injecting long esters like cypionate or Enanthate with this frequency I tend to have less side effects then once a week injections.
You wanna keep everything nice and even , not like a roller coaster going up then down over and over. This will cause more side effects and they will be harder to control.
There are a number of esters which provide varying release times. Acetate or propionate esters extend the release time of testosterone a couple of days. deconate ester prolongs the release of test about 3 weeks. Testosterone enanthate and cypionate are almost identical esters. The use of an ester allows for a less frequent injection schedule than using a water based testosterone like suspension which has no ester at all and is rapidly in and out of your system after injection. The published release times are not exact and are many times based on a single injection not many multiple injections which can delay the release of the hormone. Other factors affect release times of esters such as scar tissue and the muscle group injected. Only a blood test can confirm when the active hormone has cleared your system.
Esters not only effect release times but also the potency of the Testosterone as esters make up part of the steroid weight. This must be taken into account when calculating dosages. The longer the release time the less free hormone. For example propionate is about 15% more potent mg. for mg. then enanthate. So 500mg of propionate would equal about 575 mg. of enanthate.
Along with your testosterone you wanna take an AI.
Aromatase Inhibitor
Arimidex or Aromasin should be used on cycle to control and regulate your Estrogen. This will also help to keep free testosterone levels high.
0.5mg-1mg Arimidex eod OR 10-25mg Aromasin daily is recommended. Start with the lower dose and adjust as necessary. This can have an affect on water retention, your blood pressure, and libido. Please make adjustments as needed. Blood work is crucial for accuracy to make the proper adjustments. Free T should be in the high range and estradiol 10-25 pg/ml.
Serm
Keep nolvadex/tamoxifen on hand in case of emergency or you believe your suffering from gyno symptoms. Doses may range from 10-40mg daily depending on your test doses being used and how your body responds. Individuals will respond differently.
Human Chorionic Gonadotropin
A simple way to restore ITT levels and maintain the mass of the testes is to administer HCG during testosterone treatment. During a study it was determined that HCG is dose dependant and that approximately 300iu HCG taken every other day equal to 1,050iu HCG weekly.
I would recommend 500iu twice a week while on test.
Testosterone dose-response relationships in healthy young men
Testosterone dose-response relationships in healthy young men - PubMed
Testosterone increases muscle mass and strength and regulates other physiological processes, but we do not know whether testosterone effects are dose dependent and whether dose requirements for maintaining various androgen-dependent processes are similar. To determine the effects of graded doses...
pubmed.ncbi.nlm.nih.gov
Below is some info and stats from the study.
The only two groups that reported significant muscle building benefits were the 300 and 600 mg groups so any dose lower than 300mg will not be considered in this essay. 12 men participated in the 300 mg group and 13 men in the 600 mg group.
600mg of Testosterone a week for 20 weeks resulted in the following benefits. Increased fat free mass, muscle strength, muscle power, muscle volume, hemoglobin and IGF-1.
The same 600 mg administration resulted in 2 side effects. HDL cholesterol was negatively correlated and 2 men developed acne.
The normal range for total T in men is 241-827 ng/dl according to Labcorp and 260-1000 ng/dl according to Quest Laboratories. The normal range for IGF-1 is 81-225 according to Labcorp. Total T and IGF-1 levels were taken after 16 weeks and resulted in the following;
Total Testosterone
300 mg group-1,345 ng/dl a 691 ng increase from baseline
600 mg group-2,370 ng/dl a 1,737 ng increase from baseline
IGF-1
300 mg group-388 ng/dl a 74 ng increase from baseline
600 mg group-304 ng/dl a 77 ng increase from baseline
Body composition was measured after 20 weeks.
Fat Free Mass by underwater weighing
300 mg group-5.2kg (11.4lbs) increase
600 mg group-7.9kg (17.38lbs) increase
Fat Mass by underwater weighing
300 mg group-.5kg (1.1lbs) decrease
600 mg group-1.1kg (2.42lbs) decrease
Thigh Muscle Volume
300 mg group-84 cubic centimeter increase
600 mg group-126 cubic centimeter increase
Quadriceps Muscle Volume
300 mg group-43 cubic centimeter increase
600 mg group-68 cubic centimeter increase
Leg Press Strength
300 mg group-72.2kg (158.8lbs) increase
600 mg group-76.5kg (168.3lbs) increase
Leg Power
300 mg group-38.6 watt increase
600 mg group-48.1 watt increase
Hemoglobin
300 mg group-6.1 gram per liter increase
600 mg group-14.2 gram per liter increase
Plasma HDL Cholesterol
300 mg group-5.7 mg/dl decrease
600 mg group-8.4 mg/dl decrease
Acne
300 mg group-7 of the 12 men developed acne
600 mg group-2 of the 13 men developed acne
no significant changes in PSA or liver enzymes at any dose up to 600mg. However, long-term effects of androgen administration on the prostate, cardiovascular risk, and behavior are unknown. The study shows that there is a dose dependant relationship with testosterone administration. But keep in mind the more test your taking the greater the muscle building effects but also the greater chances of potential side effects.
An example of a cycle would look like this.
Monday 300mg Test E /12.5mg Asin (hcg500iu)
Tuesday 12.5mg Asin
Wednesday 12.5mg Asin
Thursday 300mg Test E/ 12.5mg Asin
Friday 12.5mg Asin (hcg500iu)
Saturday 12.5mg Asin/
Sunday 12.5mg Asin
If you choose to run HCG ?
PCT post cycle therapy
AI should be used as long as there is an aromatizing compound being administered. Testosterone and HCG aromatize therefore it is recommended to use an AI until they clear your system. Nolva has been shown to reduce IGF-1 and GH levels when used alone. On cycle this is not a big deal because testosterone increases IGF-1 in a dose dependant relationship. However off cycle this is a problem. PCT is a critical time and lower IGF-1 and GH levels is not something you wanna do. I am recommending an AI that is specific to men that can be used on cycle and during PCT. Aromasin is my definite choice..
Sample PCT protocol for long esters like Test C and Test E
100/100/100/50 Clomid
20mg/20mg/10mg/10mg Aromasin
3g Vit C every day
10g creatine daily
References
Testosterone dose-response relationships in healthy young men;
Testosterone dose-response relationships in healthy young men - PubMed
Testosterone increases muscle mass and strength and regulates other physiological processes, but we do not know whether testosterone effects are dose dependent and whether dose requirements for maintaining various androgen-dependent processes are similar. To determine the effects of graded doses...
pubmed.ncbi.nlm.nih.gov
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males
Abstract. Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane
academic.oup.com
Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression
Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression - PubMed
In previous studies of testicular biopsy tissue from healthy men, intratesticular testosterone (ITT) has been shown to be much higher than serum testosterone (T), suggesting that high ITT is needed relative to serum T for normal spermatogenesis in men. However, the quantitative relationship...
pubmed.ncbi.nlm.nih.gov
Use of clomiphene citrate to reverse premature andropause secondary to steroid abuse.
https://pubmed.ncbi.nlm.nih.gov/125...citrate, with multiple anabolic steroid abuse.
Hope this help some people.
Thanks macedog24
